COVID-19 and the effect of its infodemic on people’s wellbeing

In this research, it was used to look at social media behaviour during the pandemic and how it might have affected well-being. The WHO-5 Well-Being Index (WHO-5) score was used to do this. COVID-19-related material was sought for and disseminated through social media by those who participated in the study. This research shows how social media might affect people's well-being during this epidemic and other crisis in the future. 73 percent of the 993 participants were women, 91 percent were university graduates, and 50 percent worked in diverse occupations, with 20 percent working in health care. Participants said they got COVID-19-related news mostly via social media and messaging apps, with WhatsApp being the most popular. After authentication, the majority of participants said they shared information. Throughout the coronavirus pandemic, this research offers insight into the usage of Social Media and its influence on well-being. During catastrophes and disasters, social media behaviours may have an influence on public safety. There is also a need for global and local health authorities to better prepare for future challenges by developing policies and actions that address these difficulties. Social media activities may directly affect one's mental health, but more research is required before conclusions can be drawn

Promising Antimycobacterial Activities of Flavonoids against Mycobacterium sp. Drug Targets: A Comprehensive Review

Tuberculosis (TB) caused by the bacterial pathogen Mycobacterium tuberculosis (Mtb) remains a threat to mankind, with over a billion of deaths in the last two centuries. Recent advancements in science have contributed to an understanding of Mtb pathogenesis and developed effective control tools, including effective drugs to control the global pandemic. However, the emergence of drug resistant Mtb strains has seriously affected the TB eradication program around the world. There is, therefore, an urgent need to develop new drugs for TB treatment, which has grown researchers’ interest in small molecule-based drug designing and development. The small molecules-based treatments hold significant potential to overcome drug resistance and even provide opportunities for multimodal therapy. In this context, various natural and synthetic flavonoids were reported for the effective treatment of TB. In this review, we have summarized the recent advancement in the understanding of Mtb pathogenesis and the importance of both natural and synthetic flavonoids against Mtb infection studied using in vitro and in silico methods. We have also included flavonoids that are able to inhibit the growth of non-tubercular mycobacterial organisms. Hence, understanding the therapeutic properties of flavonoids can be useful for the future treatment of TB